網頁維護:蔡仁傑

更新日期:2024/03/01

研究成果 Peer-reviewed Journals

(Ma lab members in bold: graduate students#; postdocs†)

1. Wu KL#, Chen CL, Nguyen MT#, Tsai JC#Wang SC, Chiang WFHsiao PJ, Chan JS, Hou JJ, Ma N*MicroRNA regulations of vascular pathophysiology in chronic kidney disease, Clin Chim Acta. 2023
2. Wu KL#, Chou CY, Chang HY, Wu CH, Li AL#, Chen CL#Tsai JC#, Chen YF, Chen CT, Tseng CC, Chen JB, Wang IK, Hsu YJ, Lin SH, Huang CC*, Ma N*Peritoneal Effluent MicroRNA Profile for detection of Encapsulating Peritoneal Sclerosis, Clin Chim Acta. 2022
3. Nguyen MT#, Luo YH, Li AL#, Tsai JC#, Wu KL#, Chung PJ, Ma N*, miRNA as a modulator of immunotherapy and immune response in melanoma, Biomolecules, 2021, (11), 1648.  doi: 10.3390/biom11111648. Invited Review article
4. Li AL#, Chou CY, Chen CL, Wu KL#, Lin SC, Chen HC, Wang MC, Chang CC, Hsu BG, Wu MS, Ma N*, Huang CC*, The microRNA prediction models as ancillary diagnosis biomarkers for urothelial carcinoma in patients with chronic kidney disease, Front Med.(Lausanne), 2021, 8, 726214, doi: 10.3389/fmed.2021.726214. [JCR:Q1]
5. Thi Nguyen M#, Lin CH†, Liu SM#, Miyashita A, Ihn H, Lin H, Ng CH, Tsai JC#, Chen MH, Tsai MS, Lin IY#, Liu SC, Li LY, Fukushima S *, Lu J*, Ma N*, miR-524-5p reduces the progression of the BRAF inhibitor-resistant melanoma, Neoplasia, 2020, 22(12):789-799 (IF=5.696)
6. Chen CL, Yang SC, Lai CY, Wang CK, Chang CF, Lin CY, Chen WJ, Lin PY, Wu HC, Ma N, Lu FL, Lu J, CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway, Cells, 2020 Jul 16;9(7):1706. doi: 10.3390/cells9071706.
7. Chen CL#, Lin CH†, Li AL#, Huang CC, Shen BY, Chiang YU#, Fang PL#, Chang HC, Li, KL, Yang WC, Horng JT*, Ma N*,Plasma MicroRNA Profile is a Biomarker Associated with Urothelial Carcinoma in Chronic Hemodialysis Patients, Am J physiol Renal physiol, 2019,316(6):F1094-F1102 (IF=3.323, R/C=16/80 (Q1),Urology Nephrology)
8. Lin IY#, Chiou YS, Wu LC, Tsai CY, Chen CT, Chuang WC, Lee MC, Lin CC, Lin TT#, Chen SC, Pan MH*, Ma N*, CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways, Journal of Food And Drug Analysis, 2019, 27(1):184-194 (IF=4.176, R/C=13/135 (Q1), Food Science & Technology)
9. Li AL#, Chung TS, Chan YN#, Chen CL#, Lin SC, Chiang YU#, Lin CH†, Chen CC and Ma N*, microRNA expression pattern as an ancillary prognostic signature for radiotherapy, Journal of Translational medicine, 2018,16 (1): 341 (IF=4.098, R/C=41/136 (Q2), Medicine, Research & Experimental)
10. Liu SM#, Lin CH†, Lu J, Lin IY#, Tsai MS, Chen MH and Ma N*, miR-596 modulates melanoma growth by regulating cell survival and death, Journal of Investigative Dermatology, 2018, 138(4), 911-921 (IF=6.290, R/C=4/66 (Q1), Dermatology)
11. Chen WY, Ma N, Li TL, Su LJ, Chang YH, MicroRNA in situ hybridization with phosphate-methylated oligonucleotides (nDNA) probe, New Biotechology,2018, 44, S147 (IF=3.739, R/C= (Q1), Biotechology)
12. Lin IY#, Pan MH, Lai CS, Lin TT#, Chen CT, Chung TS, Chen CL, Lin CH†, Chuang WC, Lee MC, Lin CC, Ma N*, CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-κB pathways, Scientific Reports, 2017, 7(1):4862. (IF=4.122, R/C=12/64 (Q1), Multidisciplinary Sciences)
13. Hsu C-L, Chung F-H, Chen C-H, Hsu T-T, Liu S-M#, Chung D-S, Hsu Y-F, Chen C-L#, Ma N*and Lee H-C*, Genotypes of cancer stem cells characterized by epithelial-to-mesenchymal transition and proliferation related functions, (* Co-corresponding Author), Scientific Reports, 2016, 6:32523. (IF=4.259, R/C=10/64 (Q1), Multidisciplinary Sciences) 
14. Yen C-I, Liu SM#, Lo W-S , Wu J-W, Liu Y-H, Chein R-J, Yang R, Ma N*and Shieh F-K*, Cytotoxicity of Postmodified Zeolitic-Imidazolate Framework-90 (ZIF-90) Nanocrystals: Correlation between Functionality and Toxicity, (* Co-corresponding Author), Chemistry - A European Journal, 2016, 22(9):2925-9 (IF=5.317, R/C=29/166 (Q1),Chemistry, Multidisciplinary)
15. Lin S-J, Wu S-W, Chou Y-C, Lin J-H, Huang Y-C, Chen M-R, Ma N* and Tsai C-H*, Novel expression and regulation of TIMP-1 in Epstein Barr virus-infected cells and its impact on cell survival (* Co-corresponding Author), Virology 2015,481:24-3333 (IF=3.367, R/C=13/35 (Q2), Virology)
16. Wu C-C, Wu H-J, Wang C-H, Lin C-H, Hsu S-C, Chen Y-R, Hsiao M, Schuyler S C, Lu FL, Ma N, and Lu J, Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells, Cell Cycle, 2015,14(8), 1207-1217 (IF=3.952, R/C=68/187, (Q2), Cell Biology)
17. Ma N*, Lai C-H#, Chung C-H, Yang J-M, Hsu K-Cheng, Chen C-Y, Chung T-S, Li S, Ho C-T, Pan M-H*, 5-Demethyl tangeretin is more potent than tangeretin in inhibiting dimethylbenz(a) anthracene (DMBA)12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced skin tumorigenesis, (# Co-First Author), Journal of Functional Foods, 2014, 11:528-537
18. Liu SM#, Lu J, Lee, HC, Chung FH, and Ma N*, miR-524-5p suppresses growth of oncogenic BRAF melanoma by targeting BRAF and ERK2, Oncotarget, 2014, 5(19):9444-59
19. Lo W-S, Liu SM#, Wang S-C, Lin H-P, Ma N*, Huang H-Yand Shieh F-K*, A green and facile approach to obtain 100 nm zeolitic imidazolate framework-90 (ZIF-90) particles via leveraging viscosity effects (* Co-corresponding Author), RSC Advances, 2014, 4:52883-86
20. Lin CH, Wu JC, Chiou BH, Chen CH, Ma N, Chang CY, Tsen YK and Chen SC, MicroRNA regulation of DNA repair gene expression in 4-aminobiphenyl-treated HepG2 cells, Toxicology, 2014, 322:69-77 
21. Huang HN, Chen SY, Hwang SM, Yu CC, Su M-W, Mai W, Wang, HW, Cheng WC, Schuyler SC, Ma N, Lu FL, Lu J, miR-200c and GATA binding protein 4 regulate human embryonic stem cell renewal and differentiation, Stem Cell Research, 2014,12(2):338-353 
22. Chung, FH, Chiang, YR, Tseng, AL, Sung, YC, Lu, J, Huang, MC, Ma N*, Lee, HC*, Functional Module Connectivity Map (FMCM): A Framework for Searching Repurposed Drug Compounds for Systems Treatment of Cancer and an application to Colorectal Adenocarcinoma (* Co-corresponding Author), Plos One, 2014, 9(1): e86299. 
23. Chen Y-J, Thang M WC, Chan Y-T, Huang Y-F, Ma N, Yu AL, Wu C-Y, Hu M-L, Chiu K-P, Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma Cells, Plos One, 2013, 8(12): e82751. doi:10.1371 
24. Lee MF, Tsai ML, Chien LL, Cheng AC, Ma N, Ho CT, Pan MH, Phyto-Power dietary supplement potently inhibits dimethylnitrosamine-1 induced liver fibrosis in rats, Food & Function, 2013, 4(3):470-475
25. Wang CH#, Ma N*, Lin YT#, Wu CC, Hsiao M, Lu FL, Yu CC, Chen SY, Lu J. A shRNA functional screen reveals Nme6 and Nme7 are crucial for embryonic stem cell renewal. (# Co-First Author) Stem cells,2012, 30:2199–2211 
26. Chiou YS, Ma N, Sang S, Ho CT, Wang YJ, Pan MH, Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. Journal of Agricultural and Food Chemistry 2012, 60 (13), 3441-3451 
27. Mok JA, Kim PM, Lam HY, Piccirillo S, Zhou X, Jeschke G, Sheridan DL, Parker VD, Jwa M, Cameroni E, Niu H, Good M, Remenyi A, Ma NJ, et al. Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Science Signaling, 2010, 3(109):ra12 
28. Ma NJ and Stern DF. Regulation of the Rad53 Protein Kinase in Signal Amplification by Oligomer Assembly and Disassembly. Cell Cycle, 2008, 7(6): 808-817 
29. Ma JL, Lee SJ, Duong JK, and Stern DF. (2006). Activation of the Checkpoint Kinase Rad53 by the Phosphatidyl Inositol Kinase-like Kinase Mec1. J Biol Chem. 281(7):3954-63 (cited 48 times) (Note: Previous name: Ma Jia-Lin)
30. Shim EY#, Ma JL#, Oum, JH, Yanez Y, and Lee SE. (2005) The Yeast Chromatin Remodeler RSC Complex Facilitates End Joining Repair of DNA Double-Strand Breaks (# Co-First Author) Mol. Cell. Biol. 25: 3934-3944. (cited 166 times) (Note: previous name: Ma Jia-Lin)
31. Ma JL, Kim EM, Haber JE, and Lee SE. (2003) Yeast Mre11 and Rad1 Proteins Define a Ku-Independent Mechanism To Repair Double-Strand Breaks Lacking Overlapping End Sequences, Mol. Cell. Biol. 23: 8820-8828 (cited 301 times) (Note: Previous name: Ma Jia-Lin)
書目
Wang C-H, Ma N, Lin Y-T, Wu C-C, Wu H-J, Yu C-C, Hsiao M, Lu FL, Schuyler SC, and Lu J. Array-Based High Throughput Screen in Mouse Embryonic Stem Cells with shRNAs. Current Protocols in Stem Cell Biol. 2013, 26: 5C.3.1 - 5C.3.19. (Online ISBN: 9780470151808)
Professional Honors and Recognition
1. 2021, 第18屆國家新創獎-學研新創獎
2. 2021, Sliver Award, Taiwan Innotech Expo (台灣創新技術博覽會發明競賽銀牌獎)
3. 2021, Creative inventor of Taoyuan (桃園市創意發明家)
4. 2020, Platinum Award, Taiwan Innotech Expo (台灣創新技術博覽會發明競賽鉑金獎)
5. 2017-2021, Excellent Research Award, National Central University, Taiwan
專利 Patent
1. Ma N, Chang CH, Chen JB, Tseng CC, Wang IK, Chen CL, Li AL; 在腹膜透析病患中由腹腔液偵測microRNA預測腹膜硬化症之方法/ Method for estimating a risk for a subject suffering from encapsulating peritoneal sclerosis, analyzer and kit thereof; Taiwan, I740533, 2021/9/21-2040/6/10; US, 16/924,793 (applying); China 202010527704.X (applying)
2. Ma N, Chen CL, Lin CH, Li AL, Huang, CC, Chang CH, 泌尿上皮癌的檢測套組及檢測方法 / Detection Kit And Detection Method For Urothelial Carcinoma; Taiwan, I690597, 2020/04/01-2038/11/13; US 11,098,371, 2021/8/24-2039/9/3; China 201910299262.5 (applying)
3. Ma N, Huang, CC, Chang CH, Chen CL, Li AL; 評估個體罹患泌尿上皮癌之風險的方法及其套組/ Method for estimating a risk for a subject suffering from urothelial carcinoma and kit thereof; Taiwan, I718474, 2021/02/11-2039/01/30; US, 16/658,754 (applying) ; China 201910126024.4 (applying)
4. Ma N, Chung TS, Chan YN, Chen CL, Li AL; 預測癌症放射線治療之預後的分析器及方法/ Analyzer and analytical method for predicting the prognosis of cancer radiotherapy; Taiwan, I614629, 2018/2-2037/2; US 10,738,363 B2, 2017/08/30-2037/08/30
5. Ma N, Lin CH, Su HH, Chen CH, Glucose dehydrogenase and method for producing the dehydrogenase; US#62/192,074
技術移轉
1. 預測癌症放射線治療之預後的分析器及方法, 107/5/21-108/5/20, 見微生醫。